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Occurrence of a Hyperglycæmic Factor in the Corpus Cardiacum of an Insect

Abstract

ALMOST two decades have elapsed since Abramowitz et al.1 first reported the occurrence of a ‘diabetogenic’ factor in the sinus gland of a crustacean. To the best of my knowledge the experiments described here are the first to show that a substance with a similar effect occurs in the corpus cardiacum of an insect. The corpus cardiacum was selected for investigation because of its analogy to the sinus glands of Crustacea and its known content of biologically active materials2–4. In view of the recent finding that the main blood sugar in insects is the non-reducing disaccharide trehalose5–7 the effect of corpora cardiaca extracts on both reducing and non-reducing sugars in the blood has been investigated.

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STEELE, J. Occurrence of a Hyperglycæmic Factor in the Corpus Cardiacum of an Insect. Nature 192, 680–681 (1961). https://doi.org/10.1038/192680a0

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