Abstract
THE distribution of ribonucleic acid (RNA) in the subcellular structures of whole brain was studied by Brody and Bain1, and by Aldridge and Johnson2, and in the rat brain cortex during development by Keup3. We showed previously that appreciable differences exist in the distribution of nucleotides and RNA and in the incorporation of phosphorus-32 in this RNA in various brain regions4: we have now studied the RNA content of the subcellular fractions of each region of the central nervous system examined previously and the incorporation of phosphorus-32 in the RNA fractions thus isolated.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Brody, T. M., and Bain, J. A., J. Biol. Chem., 195, 685 (1952).
Aldridge, W. N., and Johnson, M. K., Biochem. J., 73, 270 (1959).
Keup, W., Ultrastructure and Cellular Chemistry of Neural Tissue, edit. by Waelsch, H., 215 (Hoeber-Harper, New York, 1957).
Mandel, P., Harth, S., and Borkowski, T., Fourth Intern. Symp. Neurochem., Varenna, 1960 (Pergamon Press, Ltd., 1961).
Hogeboom, G. H., Schneider, W. C., and Pallade, C. E., J. Biol. Chem., 172, 619 (1948).
Harth, S., Borkowski, T., Mardell, R., and Mandel, P. (in the press).
Bloor, E., J. Biol. Chem., 82, 273 (1929).
Schmidt, G., and Thannhauser, S. J., J. Biol. Chem., 161, 83 (1945).
Chauveau, J., Moule, I., and Rouiller, Ch., Bull. Soc. Chim. Biol., 39, 1521 (1957).
Georgiev, G. P., and Mantiewa, V. L., Biochimia, 25, 143 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BORKOWSKI, T., HARTH, S., MARDELL, R. et al. Distribution of Ribonucleic Acid in Subcellular Fractions of Various Regions of the Central Nervous System of the Rat. Nature 192, 456–457 (1961). https://doi.org/10.1038/192456a0
Issue Date:
DOI: https://doi.org/10.1038/192456a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.