A Relation between the Reactivity of Human Red Cells to Antiglobulin Tests and their Surface Structure

Abstract

SEVERAL authors1 have suggested that changes in the immunological reactivity of a cell may be correlated with changes in its surface structure. We present evidence here that human red cells giving a positive antiglobulin reaction show changes in their surfaces demonstrable with the electron microscope.

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References

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    Liu, C. K., and Evans, R. S., Proc. Soc. Exp. Biol. and Med., 79, 194 (1952). Rebuck, J. W., Anat. Rec, 115, 4 (1953). de Vries, A., et al., Harefuah (J. Med. Assoc. Israel) (Jan. 1, 1957). Goldberg, B., and Green, N., J. Exp. Med., 109 (5), 505 (1959).

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    Hillier, J., and Hoffmann, J. F., J. Cell. Comp. Physiol., 42, 203 (1953).

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    Green, H. N., Wakefield, S., and Littlewood, G., Brit. Med. J., ii, 779 (1957).

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DAVIS, J., GREEN, H. & TYMMS, P. A Relation between the Reactivity of Human Red Cells to Antiglobulin Tests and their Surface Structure. Nature 191, 923–924 (1961). https://doi.org/10.1038/191923a0

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