Infectious Ribonucleic Acids derived from Mouse Brains infected with Two Kinds of Arbor Virus Group B

Abstract

INFECTIOUS ribonucleic acid (RNA) has been extracted by phenol treatment1 from cells infected with animal viruses. In Group B of the arbor viruses, it has been recently reported that the RNA extracted from mouse brain infected with Murrary Valley encephalitis virus2 or Japanese B virus3 and from Ehrlich ascites tumour cells infected with West Nile encephalitis4 are infectious. The purpose of this present communication is to add a datum concerning the extraction of infectious RNA from mouse brains infected with dengue fever virus to the reports of viral RNA already published, and to compare the effects of cold- and hot-phenol extractions on the yields of infectious RNA from the cells infected with Japanese B encephalitis virus and dengue fever virus, respectively.

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References

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NAKAMURA, M. Infectious Ribonucleic Acids derived from Mouse Brains infected with Two Kinds of Arbor Virus Group B . Nature 191, 624 (1961). https://doi.org/10.1038/191624a0

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