Action of the Hypothalamus


EXPERIMENTS with an analogue model of the heart, demonstrated by me1, show that a pulse may arise, in a fluid-filled elastic system, in either of two ways : in the first, energy is cycled into the system from a mechanical source, corresponding to the physico-chemical contraction of the ventricles ; in the second, pulsation can be derived from the static head of pressure with the aid of a length of elastic tubing arranged as a wave guide. The latter device, termed an ‘oscillator’, may be employed to time delivery of energy from the external source, in such a manner that the system is self-oscillating and that the two pulses, of differing origin, are synchronous.

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  1. 1

    Malcolm, J. E., Proc. Physiol. Soc. (March 24, 1961).

  2. 2

    Malcolm, J. E., Nature, 190, 1114 (1961).

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MALCOLM, J. Action of the Hypothalamus. Nature 191, 606 (1961).

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