Letter | Published:

Anaphylactoid Reaction in Rats

Naturevolume 191pages399400 (1961) | Download Citation



THE primary injection of dextran or egg white into rats produces hyperæmia, pruritus, and œdema of the face, tongue and paws ; symptoms of the so-called anaphylactoid reaction1. While studying factors which modify this reaction, it became apparent that a proportion of rats failed to show this response. This problem was therefore examined in detail.

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  1. 1

    Selye, Endocrinology, 21, 169 (1937).

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    • J. M. HARRIS

    Present address: School of Pharmacy, Brighton Technical College,


  1. Department of Pharmacology, School of Pharmacy, University of London, 29–39 Brunswick Square, London, W.C.1

    • J. M. HARRIS
    •  & G. B. WEST


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