Abstract
THE ability of influenza viruses and receptor-destroying enzyme from Vibrio cholerae to inactivate human erythrocyte agglutinogens M and N was first noted in this Laboratory1 and afterwards independently in Finland2. Lu a and Lu b agglutinogens are also inactivated by influenza viruses but not by the receptor-destroying enzyme3. None of 17 additional human blood group agglutinogens—including S and s which are considered to be products of genes very closely linked to the M and N genes—was destroyed by these agents1,3. On the other hand, the inactivation of a number of erythrocyte agglutinogens including M and N by papain, trypsin and other enzymes has been known for a considerable time4–6.
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SPRINGER, G., STALDER, K. Action of Influenza Viruses, Receptor-destroying Enzyme and Proteases on Blood Group Agglutinogen M g . Nature 191, 187–188 (1961). https://doi.org/10.1038/191187a0
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DOI: https://doi.org/10.1038/191187a0
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