Abstract
IN searching for an experimental animal which, in regard to its steroid metabolism, would be suitable for an investigation into the mechanism of action of certain synthetic steroids, particularly 19-norsteroids, we decided to use the domestic pig. A few preliminary experiments were made, during which we determined, among other things, the concentration of Zmimermann chromogens in the urine of male and female pigs and in the urine of castrated animals, while the influence of chorionic gonadotrophin and adrenocorticotrophic hormone on the excretion of Zimmermann chromogens in adult male pigs was also determined. After these preliminary experiments we started to isolate and identify the substances which produce the Zimmer-mann reaction.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Dingemanse, E., Huis in 't Veld, L. G., and de Laat, B. M., J. Clin. Endocrinol., 6, 535 (1946).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HUIS IN 'T VELD, L., LOUWERENS, B. & REILINGH, W. Neutral 17-Ketosteroids in Porcine Urine. Nature 191, 175–176 (1961). https://doi.org/10.1038/191175a0
Issue Date:
DOI: https://doi.org/10.1038/191175a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
