Letter | Published:

Role of the Lung in Metabolism of Fat during Ontogeny of the Rat

Naturevolume 191pages8586 (1961) | Download Citation



MILK of the rat contains up to 20 cer cent fat1, and the gastro-intestinal tract of infant rats absorbs fat more rapidly than that of adult animals2. The cells of the intestinal mucosa of infant rats after a meal contain much more neutral fat than those of adult animals where more ‘acid lipids’ are found3 (using nile blue). This, together with a lower intestinal esterase activity in infant rat intestine3, indicates a different absorption and perhaps transport of fat. Since fat transported via lymphatic pathways must pass through the lungs before entering the blood, it was thought pertinent to examine this organ histo-chemically during ontogeny of the rat.

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  1. 1

    Glass, R. L. (dissertation, University of Minnesota, 1956).

  2. 2

    Koldovský, O., Hahn, P., Jiránek, J., and Tintěra, J., Čs. fysiol., 8, 211 (1959).

  3. 3

    Anisimova, E., Vacek, Z., Koldovský, O., and Hahn, P., Čs. fysiol., 8, 392 (1959).

  4. 4

    Schrade, W., and Biegler, R., Klinische Wochenschrift, 34, 1247 (1956).

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  1. Institute of Embryology, Charles University, Institute of Physiology, Czechoslovak Academy of Sciences, Prague

    • Z. VACEK
    • , P. HAHN
    •  & O. KOLDOVSKÝ


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