Abstract
IT has been shown1 that during a prolonged stay at altitudes above 15,000 ft. there is an increase in the salivary excretion of sodium and a decrease in that of potassium. In one subject this change in salivary electrolyte composition showed a marked acclimatization effect (Fig. 1). These findings suggested that, on arrival at a high altitude, the level of circulating aldosterone was likely to be greatly reduced, but that there would probably be a tendency for it to return slowly towards normal values with passage of time.
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References
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Ayres, P. J., Garrod, O., Simpson, S. A., and Tait, J. F., Biochem. J., 65, 639 (1957).
Rundo, J., Proc. Second Int. Conf. Peaceful Uses of Atomic Energy, 23, 101 (1958).
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AYRES, P., HURTER, R., WILLIAMS, E. et al. Aldosterone Excretion and Potassium Retention in Subjects living at High Altitude. Nature 191, 78–80 (1961). https://doi.org/10.1038/191078b0
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DOI: https://doi.org/10.1038/191078b0
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