Letter | Published:

Aldosterone Excretion and Potassium Retention in Subjects living at High Altitude

Naturevolume 191pages7880 (1961) | Download Citation



IT has been shown1 that during a prolonged stay at altitudes above 15,000 ft. there is an increase in the salivary excretion of sodium and a decrease in that of potassium. In one subject this change in salivary electrolyte composition showed a marked acclimatization effect (Fig. 1). These findings suggested that, on arrival at a high altitude, the level of circulating aldosterone was likely to be greatly reduced, but that there would probably be a tendency for it to return slowly towards normal values with passage of time.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Williams, E. S., Clin. Sci., 21, 37 (1961).

  2. 2

    Williams, E. S., and Edwards, R., Middlesex Hosp. J., 60, 167 (1960).

  3. 3

    Ayres, P. J., Garrod, O., Simpson, S. A., and Tait, J. F., Biochem. J., 65, 639 (1957).

  4. 4

    Rundo, J., Proc. Second Int. Conf. Peaceful Uses of Atomic Energy, 23, 101 (1958).

Download references

Author information


  1. Barnato-Joel Laboratories, The Middlesex Hospital Medical School, London, W.1

    • P. J. AYRES
    • , RONA C. HURTER
    •  & E. S. WILLIAMS
  2. Atomic Energy Research Establishment, Harwell, Berkshire

    • J. RUNDO


  1. Search for P. J. AYRES in:

  2. Search for RONA C. HURTER in:

  3. Search for E. S. WILLIAMS in:

  4. Search for J. RUNDO in:

About this article

Publication history

Issue Date



Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.