Letter | Published:

Aldosterone Excretion and Potassium Retention in Subjects living at High Altitude

Naturevolume 191pages7880 (1961) | Download Citation

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Abstract

IT has been shown1 that during a prolonged stay at altitudes above 15,000 ft. there is an increase in the salivary excretion of sodium and a decrease in that of potassium. In one subject this change in salivary electrolyte composition showed a marked acclimatization effect (Fig. 1). These findings suggested that, on arrival at a high altitude, the level of circulating aldosterone was likely to be greatly reduced, but that there would probably be a tendency for it to return slowly towards normal values with passage of time.

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References

  1. 1

    Williams, E. S., Clin. Sci., 21, 37 (1961).

  2. 2

    Williams, E. S., and Edwards, R., Middlesex Hosp. J., 60, 167 (1960).

  3. 3

    Ayres, P. J., Garrod, O., Simpson, S. A., and Tait, J. F., Biochem. J., 65, 639 (1957).

  4. 4

    Rundo, J., Proc. Second Int. Conf. Peaceful Uses of Atomic Energy, 23, 101 (1958).

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Affiliations

  1. Barnato-Joel Laboratories, The Middlesex Hospital Medical School, London, W.1

    • P. J. AYRES
    • , RONA C. HURTER
    •  & E. S. WILLIAMS
  2. Atomic Energy Research Establishment, Harwell, Berkshire

    • J. RUNDO

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https://doi.org/10.1038/191078b0

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