A New Technique of Chromatography and Ionophoresis on Ion-exchange Paper: Application to the Separation of Barbiturate, Salicylate and Acetophenetidin

Abstract

WE have found that, when a mixture containing barbiturate, salicylate and acetophenetidin is subjected to chromatography on Whatman No. DE20 cellulosic ion-exchange paper in dilute ammonia solution, a partial resolution of the components is possible. Salicylate is clearly separated from the other two compounds, which move together with only partial resolution (Fig. 1).

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References

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    Goldbaum, L., Toxicology, edit. by Stewart, C. P., and Stolman, A., 1 (Academic Press, New York, 1960).

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STREET, H., NIYOGI, S. A New Technique of Chromatography and Ionophoresis on Ion-exchange Paper: Application to the Separation of Barbiturate, Salicylate and Acetophenetidin. Nature 190, 537–538 (1961). https://doi.org/10.1038/190537a0

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