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Reduction of Coenzyme Q by Succinic Acid Dehydrogenase

Abstract

Crane, Hatefi, Lester and Widmer1,2 have shown that coenzyme Q is reduced by mitochondria or derivative particles like electron-transporting particles, or succinic dehydrogenase complex, and that this reaction is sensitive to antimycin A. We have now succeeded in reducing coenzyme Q with a soluble preparation of succinic acid dehydrogenase, and this reaction was not sensitive to antimycin A.

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References

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    Crane, F. L., Hatefi, Y., Lester, R. L., and Widmer, C., Biochim. Biophys. Acta, 25, 220 (1957).

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HELLER, J., SZARKOWSKA, L. & PETRYSZYN, C. Reduction of Coenzyme Q by Succinic Acid Dehydrogenase. Nature 189, 578–579 (1961). https://doi.org/10.1038/189578a0

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