An Effect of Tritiated Thymidine on the Incorporation of Thymidine into Chromosomal Deoxyribonucleic Acid

Abstract

IN the course of a series of experiments designed to test for possible anomalies in the synthesis and behaviour of chromosomal deoxyribonucleic acid resulting from the use of tritiated thymidine, the possibility arose that the tritiated precursor could interfere with the normal course of synthesis and partition by destroying the integrity of the deoxyribonucleic acid molecule or otherwise modifying the normally operative control mechanisms. This possibility was examined by comparing the incorporation of thymidine labelled with carbon-14 into meristematic cells in the presence and absence of tritiated thymidine.

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KRAUSE, M., PLAUT, W. An Effect of Tritiated Thymidine on the Incorporation of Thymidine into Chromosomal Deoxyribonucleic Acid. Nature 188, 511–512 (1960). https://doi.org/10.1038/188511b0

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