Presynaptic Nature of Neuromuscular Depression in the Frog

Abstract

WHEN a number of successive nerve impulses arrive at a curarized neuromuscular junction, the induced end-plate potentials show a gradual decrease in size (Wedensky-inhibition, or junctional fatigue). Two different mechanisms, though not exclusive of each other, are conceivable.

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References

  1. 1

    Feng, T. P., Chin. J. Physiol., 16, 341 (1941).

  2. 2

    Eccles, J. C., “The Neurophysiological Basis of Mind” (Oxford, Clarendon Press, 1953).

  3. 3

    Castillo, J. del, and Katz, B., J. Physiol., 124, 574 (1954).

  4. 4

    Takeuchi, A., Jap. J. Physiol., 8, 102 (1958).

  5. 5

    Thesleff, S., J. Physiol., 148, 659 (1959).

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OTSUKA, M., ENDO, M. Presynaptic Nature of Neuromuscular Depression in the Frog. Nature 188, 501–502 (1960). https://doi.org/10.1038/188501a0

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