Abstract
THE presence of the thyroid gland appears to be necessary for prolonged survival of the cold-acclimatized rat1,2. Rats in the cold also appear to turn over iodine-131 more rapidly than normal3–6, indicating a more rapid than normal accumulation of iodide and release of thyroid hormone. Since oxidative phosphorylation, a process thought by some7–10 to be regulated by the thyroid, has been noted to be partially uncoupled11–13, as well as physically and biochemically more labile in the cold-acclimatized rat12,14, we have investigated the alteration of mitochondrial function following thyroidectomy of cold-exposed and normal rats.
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LIANIDES, S., BEYER, R. Thyroid Function and Oxidative Phosphorylation in Cold-exposed Rats. Nature 188, 1196–1197 (1960). https://doi.org/10.1038/1881196a0
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DOI: https://doi.org/10.1038/1881196a0
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