Letter | Published:

Effect of Three Compounds related to Diethylstilbœstrol on the Phagocytic Activity of the Reticulo-Endothelial System

Naturevolume 187pages10321033 (1960) | Download Citation



IT has been reported previously that diethylstilbœstrol is a strong stimulant of the phagocytic activity of the reticulo-endothelial system1; that the minimum dose required to stimulate the phagocytes is about 100 times greater than that necessary to induce œstrus2; and that after treatment with 0.5 mgm. diethylstilbœstrol daily for six days the phagocytic activity returns to within normal control limits in about eight days3.

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  1. 1

    Nicol, T., Bilbey, D. L. J., and Ware, C. C., Nature, 181, 1538 (1958).

  2. 2

    Nicol, T., and Ware, C. C., Nature, 185, 42 (1960).

  3. 3

    Ware, C. C., and Nicol, T., Nature, 186, 974 (1960).

  4. 4

    Biozzi, G., Benacerraf, B., and Halpern, B. N., Brit. J. Exp. Path., 34, 441 (1953).

  5. 5

    Halpern, B. N., Biozzi, G., Nicol, T., and Bilbey, D. L. J., Nature, 180, 503 (1957).

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  1. Department of Anatomy, King's College, London, W.C.2.

    • T. NICOL
    • , G. BROWNLEE
    • , C. DRUCE
    •  & C. C. WARE


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