Abstract
SEVERAL attempts have been made in the past to correlate the amount of acetylcholine released during activity at nerve endings with the amount needed to produce activation of the effector cell1–3. It is clearly of crucial importance for the acetylcholine hypothesis that there should be quantitative agreement between these amounts. Until recently, a very substantial discrepancy has remained, supporting the suggestion that acetylcholine is merely a byproduct of transmission. One source of difficulty in making such correlations has been the paucity of results concerning the release of acetylcholine and the excitation produced by its application in the same preparation.
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KRNJEVIĆ, K., MITCHELL, J. Release of Acetylcholine in Rat Diaphragm. Nature 186, 241 (1960). https://doi.org/10.1038/186241a0
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DOI: https://doi.org/10.1038/186241a0
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