Labelling of Rose Bengal with Iodine-131 by Radioactive Exchange

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THE most widely used test for the chromoexcretive ability of the polygonal liver cells is the clearance test with rose bengal. The scope of the method was increased considerably by Taplin et al. 1,2 who introduced the use of labelled rose bengal. The test achieved great diagnostic value in cases of obstructional and toxic damage. We have been able to improve the method for preparing rose bengal labelled with iodine–131.

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  1. 1

    Lowenstein, G. M., Proc. Soc. Exp. Biol Med., 93, 377 (1956).

  2. 2

    Taplin, G. V., Meredith, O. M., Jnr., and Kade, H., J. Lab. Clin. Med., 45, 665 (1955).

  3. 3

    Renault, H., Jacquier, C., Jemmet, H., and Jammet, J., Proc. First Unesco Int. Conf. Paris, 3, 719 (1957).

  4. 4

    Liebster, J., Kácl, J., and Babický, A., Nature, 183, 1474 (1959).

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LIEBSTER, J., ANDRYSEK, O. Labelling of Rose Bengal with Iodine-131 by Radioactive Exchange. Nature 184, 913 (1959) doi:10.1038/184913a0

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