Letter | Published:

Excitability and Phosphorylation of Muscle and Nerve in Sodium-free Hydrazinium Solution


THE electrical activity of frog skeletal muscle was found to be maintained in a sodium-free hydrazinium solution1,2. In addition, excitability of ventral nerve roots was normal in a hydrazinium solution (unpublished). A series of studies were undertaken to determine the influence of hydrazine on the biochemical properties of conductive tissues, and this communication is concerned specifically with phosphorylation and energy synthesis.

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  1. 1

    Koketsu, K., and Nishi, S., Nature, 182, 887 (1958).

  2. 2

    Koketsu, K., and Nishi, S., J. Physiol. (in the press).

  3. 3

    Abood, L. G., and Goldman, E., Amer. J. Physiol., 184, 329 (1956).

  4. 4

    Abood, L. G., Goldman, E., and Lipman, V., J. Neurochem., 2, 318 (1958).

  5. 5

    Ling, G., in “Phosphorus Metabolism”, W. D. McElroy and Glass, 2, 748 (Johns Hopkins, Baltimore, 1952).

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