Abstract
IN crosses between Salmonella typhimurium strain LT-7 and Escherichia coli strain K-12 Hfr, it was found that recombination occurred only when the Salmonella strain carried a mutator factor, presumably1 a mutator gene (mut). Earlier studies had shown that the main effect of mut is to increase the rate of spontaneous mutation of virtually all genes with which it was tested2.
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References
Miyake, T., and Demerec, M., Nature, 183, 1586 (1959).
Demerec, M., Lahr, E. L., Miyake, T., Goldman, I., Balbinder, E., Banic, S., Hashimoto, K., Glanville, E. V., and Gross, J. D., Carnegie Inst. Wash. Yr. Bk., 57, 390 (1958).
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Hayes, W., Cold Spring Harbor Symposia Quant. Biol., 18, 75 (1953).
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MIYAKE, T. Fertility Factor in Salmonella typhimurium . Nature 184, 657–658 (1959). https://doi.org/10.1038/184657a0
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DOI: https://doi.org/10.1038/184657a0
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