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Bence Jones Proteinuria Associated with a Transplantable Mouse Plasma-Cell Neoplasm

Nature volume 184, pages 654–655 (1959)Cite this article

An Erratum to this article was published on 10 October 1959

Abstract

IN 1848 Bence Jones reported his unique findings in the urine of a grocer who had a malignant disease involving the bones, afterwards identified as multiple myeloma1. Bence Jones described a protein material which precipitated on heating of the acidified urine, became soluble on boiling and reprecipitated on cooling. Recent studies are in general agreement that proteins with these unusual solubility properties are present in the urine of about 50 per cent of patients with malignant plasmacytomas (multiple myeloma)2.

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References

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Authors and Affiliations

  1. National Cancer Institute, National Institutes of Health, U.S. Public Health Service, Bethesda, Md.

    JOHN L. FAHEY & MICHAEL POTTER

Authors
  1. JOHN L. FAHEY
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  2. MICHAEL POTTER
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FAHEY, J., POTTER, M. Bence Jones Proteinuria Associated with a Transplantable Mouse Plasma-Cell Neoplasm. Nature 184, 654–655 (1959). https://doi.org/10.1038/184654a0

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