Abstract
IN the ten years that have passed since Szent-Györgyi1 introduced the use of the glycerol-extracted muscle fibre, it has proved extremely useful for investigating the molecular events underlying muscular contraction. Usually, the fibre has been regarded as a ‘contractile skeleton’ ; on this basis its response to a chemical agent has commonly been interpreted as a direct response of the contractile elements, rather than an effect mediated or influenced by other still functional components of the muscle cell.
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References
Szent-Györgyi, A., Biol. Bull., 96, 140 (1949).
Perry, S. V., Physiol. Rev., 36, 1 (1956).
Molnar, J., and Lorand, L., Nature, 183, 1032 (1959). Briggs, F. N., Kaldor, G., and Gergely, J., Biochim. Biophys. Ada, 34, 211 (1959).
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WILSON, J., ELLIOTT, P., GUTHE, K. et al. Oxygen Uptake of Glycerol-extracted Muscle Fibres. Nature 184, 1947 (1959). https://doi.org/10.1038/1841947a0
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DOI: https://doi.org/10.1038/1841947a0
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