Abstract
VANCOMYCIN, an antibiotic obtained from Streptomyces orientalis, is effective against a number of growing bacteria, particularly those which are Gram-positive. Mutation to resistance towards this compound is of a very low order, and the antibiotic has been shown to be clinically effective against strains of Staphylococcus aureus which are resistant to the more common antibiotics.
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References
Gale, E. F., and Folkes, J. P., Biochem. J., 53, 483 (1953).
Gale, E. F., “Harvey Lectures”, 51, 25 (1957).
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JORDAN, D., INNISS, W. Selective Inhibition of Ribonucleic Acid Synthesis in Staphylococcus aureus by Vancomycin. Nature 184, 1894–1895 (1959). https://doi.org/10.1038/1841894b0
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DOI: https://doi.org/10.1038/1841894b0
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