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Pathway of Carbon-14 Incorporation from NaH14CO3 to Hæm in Duck Blood incubated in vitro

Abstract

PREVIOUSLY we have found that the hæm synthesized by duck blood in the presence of NaH14CO3 was radioactive1 and that radioactive ketoacids, namely pyruvic and α-ketoglutaric acids were formed2. We suggested that Krebs' cycle was effective for the incorporation of carbon-14 into hæm via succinic acid. We have extended our experiments to prove this hypothesis.

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References

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BRECCIA, A., FANTOLA, A., LAZZARINI, E. et al. Pathway of Carbon-14 Incorporation from NaH14CO3 to Hæm in Duck Blood incubated in vitro . Nature 184, 1879–1880 (1959). https://doi.org/10.1038/1841879a0

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