Abstract
UNSTABLE products were formed from certain cytosine derivatives on ultra-violet irradiation. These products had a new band at ∼240 mµ and lacked the characteristic ∼270 mµ maxima of cytosine derivatives. The products were not only reconstituted to their original compounds in the presence of acid and base but also spontaneously reconstituted themselves on standing, as indicated by the reversion of the ultra-violet spectra2. Therefore, in these respects the cytosines differ from the uracils1,8.
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References
Part I of this series, J. Amer. Chem. Soc., 80, 6196 (1958); Part II, ibid., 80, 6199 (1958); also ibid., 78, 4180 (1956).
Sinsheimer, R. L., Radiation Res., 6, 121 (1957). Wierzchowski, K. L., and Shugar, D., Biochim. Biophys. Acta, 25, 355 (1957).
Marshall, J. R., and Walker, J., J. Chem. Soc., 1004 (1951). Brown, D. J., Hoerger, E., and Mason, S. F., ibid., 211 (1955).
Wang, S. Y., Nature (in the press).
Batt, R. D., Martin, J. K., Ploeser, J. McT., and Murray, J., J. Amer. Chem. Soc., 76, 3663 (1954).
Fox, J. J., and Shugar, D., Bull. Soc. Chim. Belg., 61, 44 (1952).
Shugar, D., and Fox, J. J., Biochim. Biophys. Acta, 9, 199 (1952).
Moore, A. M., and Thomas, C. H., Science, 122, 594 (1955); Can. J. Chem., 35, 163 (1957).
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WANG, S. Phototautomerization of Cytosine Derivatives on Ultra-violet Irradiation1 . Nature 184, 184–185 (1959). https://doi.org/10.1038/184184a0
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DOI: https://doi.org/10.1038/184184a0
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