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Hormone Effects on Early Distribution and Disappearance from the Blood of Promethium-147 in Rats

Abstract

GROWTH hormone, as well as cortisone, has been shown to alter metabolic balances and tissue distribution of potassium and sodium1. With injected calcium-45, growth hormone restored the diminished uptake by bone observed in hypophysectomized rats, but in normal rats it had no effect on uptake of calcium-452. The present work with normal rats demonstrates effects of growth hormone and cortisone on early uptake by tissue and on disappearance from the blood with time of the lanthanide fission metal promethium-147.

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References

  1. Stein, J. D., jun., Bennett, L. L., Batts, A. A., and Li, C. H., Amer. J. Physiol., 171, 587 (1952).

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  2. Ulrich, F., Beinhardt, W. O., and Li, C. H., Acta Endocrinol., 10, 117 (1952).

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KAWIN, B. Hormone Effects on Early Distribution and Disappearance from the Blood of Promethium-147 in Rats. Nature 184, 1816–1817 (1959). https://doi.org/10.1038/1841816b0

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  • DOI: https://doi.org/10.1038/1841816b0

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