Abstract
SEVERAL vasoconstrictor compounds have been shown to protect animals against lethal doses of X-radiation. A review of this field has recently been prepared by Pihl and Eldjarn1. Methoxamine, β-hydroxy, β-(2,5-dimethoxyphenyl)-iso-propylamine, is a compound with pronounced vasoconstrictor properties2 which does not appear to have been previously tested against radiation. We wish to report the radioprotective action of methoxamine hydrochloride (‘Vasoxine’, Burroughs Wellcome) in mice.
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References
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SMITH, A., ASHWOOD-SMITH, M. & LOWMAN, D. Radioprotective Action of Methoxamine. Nature 184, 1729–1730 (1959). https://doi.org/10.1038/1841729a0
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DOI: https://doi.org/10.1038/1841729a0
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