Abstract
IT is reasonable to think that there are stimuli and opportunities in every human life which result in a cancerous transformation of some cells. The main factor in the progress of these cells to the clinical tumour stage might be a deficiency in the growth-controlling defensive mechanism. To demonstrate the possible existence of such factors we have studied since 1955 the effect of human serum on different cells in cell culture1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Penttinen, K., and Saxén, E., Ann. Med. Exp. Fenn., 34, 22 (1956); 34, 396 (1956); 35, 335 (1957). Penttinen, K., Saxén, E., Saxén, L., Toivonen, S., and Vainio, T., ibid., 36, 27 (1958).
Vainio, T., and Pentteinen, K., ibid., 37, 18 (1959).
Cailleau, R., and Kirk, P. L., Texas Rep., 2, 237 (1957). Bolande, R. P., and Todd, E. W., Arch. Path., 66, 720 (1958). Fedoroff, S., J. Lab. Clin. Med., 48, 55 (1956).
Norris, E. R., and Majnarich, J. J., Amer. J. Phsiol., 153, 492 (1948).
Southam, C. M., Moore, A. E., and Rhoads, C. P., Proc. Amer. Ass. Cancer Res., 2, 251 (1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PENTTINEN, K., SAXÉN, E. Growth-Controlling Action of Human Serum in Cell Culture. Nature 184, 1570–1571 (1959). https://doi.org/10.1038/1841570b0
Issue Date:
DOI: https://doi.org/10.1038/1841570b0
This article is cited by
-
In vitro culture of bovine fibroblasts using select serum-free media supplemented with Chlorella vulgaris extract
BMC Biotechnology (2023)
-
Production and action of interferon in HeLa cells
Archiv f�r die gesamte Virusforschung (1961)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.