Letter | Published:

Effect of Ultrasound on the Protein of Human Serum Denatured with Tannin

Abstract

TANNIN—the natural tannin glycoside ester which occurs in many plants—is a weakly acidic compound. An aqueous solution of tannin gives an insoluble precipitate with solutions of salts of heavy metals, and with solutions of organic substances, such as alkaloids, gelatine and protein. Numerous investigators have studied these complexes, using various means to break them up. We have used ultrasonic vibration, with which we previously broke up the tannin-alkaloid complex in an alcoholic extract quinine bark.1 Other workers3 have studied the effect of ultrasound on the structure of organic substances, particularly molecular size. The present work was concerned with the complex of tannin with human serum protein.

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References

  1. 1

    Adamski, R., and Mizgalski, W., Acta Pol. Pharm., XIV (2), 119 (1952).

  2. 2

    Auerswald, W., and Bornschein, H., Naturwiss., 37, 524 (1950).

  3. 3

    Kanig, K., and Künkel, H., Hoppe-Seyler's Z. Physiol. Chem., 309, 162, 166, 171 (1958). Kanig, K., ibid., 309, 176 (1958).

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