Letter | Published:

Effect of Ultrasound on the Protein of Human Serum Denatured with Tannin


TANNIN—the natural tannin glycoside ester which occurs in many plants—is a weakly acidic compound. An aqueous solution of tannin gives an insoluble precipitate with solutions of salts of heavy metals, and with solutions of organic substances, such as alkaloids, gelatine and protein. Numerous investigators have studied these complexes, using various means to break them up. We have used ultrasonic vibration, with which we previously broke up the tannin-alkaloid complex in an alcoholic extract quinine bark.1 Other workers3 have studied the effect of ultrasound on the structure of organic substances, particularly molecular size. The present work was concerned with the complex of tannin with human serum protein.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Adamski, R., and Mizgalski, W., Acta Pol. Pharm., XIV (2), 119 (1952).

  2. 2

    Auerswald, W., and Bornschein, H., Naturwiss., 37, 524 (1950).

  3. 3

    Kanig, K., and Künkel, H., Hoppe-Seyler's Z. Physiol. Chem., 309, 162, 166, 171 (1958). Kanig, K., ibid., 309, 176 (1958).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.