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Separation of Prealbumins by Starch Gel Electrophoresis

Abstract

SEPARATION of complex protein mixtures can be achieved by electrophoresis in starch gel1–3, the resolving power of which can be further increased by substituting for the routinely employed borate buffer a discontinuous system of buffers4,5. Smithies has recently improved the resolution by applying serum directly into wells cast in the gel and performing the electrophoresis with the gel in the vertical position6.

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References

  1. Smithies, O., Biochem. J., 61, 629 (1955).

    Article  CAS  Google Scholar 

  2. Poulik, M. D., and Smithies, O., Biochem. J., 68, 636 (1958).

    Article  CAS  Google Scholar 

  3. Poulik, M. D., Nature, 177, 982 (1956).

    Article  ADS  CAS  Google Scholar 

  4. Poulik, M. D., Nature, 180, 1477 (1957).

    Article  ADS  CAS  Google Scholar 

  5. Harris, H., Robson, E. B., and Siniscalco, M., Nature, 182, 452 (1958).

    Article  ADS  CAS  Google Scholar 

  6. Smithies, O., Biochem. J., 71, 585 (1959).

    Article  CAS  Google Scholar 

  7. Poulik, M. D., J. Immunol. (in the press).

  8. Schultze, H. E., Schönenberger, M., and Schwick, G., Biochem. Z., 267 1956).

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POULIK, M. Separation of Prealbumins by Starch Gel Electrophoresis. Nature 184, 1067–1068 (1959). https://doi.org/10.1038/1841067a0

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  • DOI: https://doi.org/10.1038/1841067a0

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