Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Abolition by Chlorpromazine of the Inhibiting Effect of Iproniazid on the Depletion of Adrenal Catechol Amines induced by Reserpine

Abstract

IT is well known that reserpine induces a decrease of catechol amines in the adrenal medulla1–5. In the rat pretreatment with iproniazid, a monoamine oxidase inhibitor, completely overcomes this catechol amine depletion6–8.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Carlsson, A., and Hillarp, N. A., Kungl. Fhysiogr. Sällsk. Lund. Förh., 8, 26 (1956).

    Google Scholar 

  2. Kroneberg, G., and Schümann, H. J., Arzneimittelforschung, 4, 279 (1957).

    Google Scholar 

  3. Molinatti, G. M., Camanni, F., and Losana, O., Arch. Int. Pharmacodyn., 116, 483 (1958).

    CAS  PubMed  Google Scholar 

  4. Camanni, F., Losana, O., and Molinatti, G. M., Experientia, 4, 199 (1958).

    Article  Google Scholar 

  5. Camanni, F., and Molinatti, G. M., Acta Endocrinol., 29, 369 (1958).

    Article  CAS  Google Scholar 

  6. Holtz, P., Balzer, H., and Westermann, E., Arch. Exp. Path. Pharmak., 231, 361 (1957).

    CAS  Google Scholar 

  7. Zbinden, G., and Studer, A., Experientia, 14, 201 (1958).

    Article  CAS  Google Scholar 

  8. Camanni, F., Losana, O., Molinatti, G. M., and Olivetti, M., Arch. Int. Pharmacodyn. (in the press).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CAMANNI, F., MOLINATTI, G. & OLIVETTI, M. Abolition by Chlorpromazine of the Inhibiting Effect of Iproniazid on the Depletion of Adrenal Catechol Amines induced by Reserpine. Nature 184, BA65–BA66 (1959). https://doi.org/10.1038/184065a0b

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/184065a0b

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing