Abstract
IT has been repeatedly reported that isolated mitochondria maintain a low water content if incubated in conditions favourable to oxidative phosphorylation1–5. Di Sabato and Fonnesu6,7 found that this happens only when certain metabolites are used as the oxidizable substrate, for example, succinate, α-ketoglutarate and glutamate.
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References
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DI SABATO, G. Effect of Reduced Diphosphopyridine Nucleotide on the Swelling of Isolated Mitochondria. Nature 183, 997–998 (1959). https://doi.org/10.1038/183997a0
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DOI: https://doi.org/10.1038/183997a0
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