Abstract
ISOLATED lampbrush chromosomes from the oocytes of many vertebrates have been subjected to various treatments to obtain information about the basic structure and organization of chromosomes. Lamp-brush chromosomes are ideally suited for studies of this kind for they are long (350–850µ), easily isolated and can be treated without fixation and viewed immediately with an inverted phase microscope system1,2. This enables the experimenter to observe the action of the reagents upon the chromosomes soon after treatment and with minimum handling.
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AMAROSE, A. Some Effects of Colchicine on Lampbrush Chromosomes. Nature 183, 975–976 (1959). https://doi.org/10.1038/183975a0
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DOI: https://doi.org/10.1038/183975a0
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