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Effect of Dietary Protein on the Severity of Experimental Mouse Hepatitis

Nature volume 183, pages 609–610 (1959)Cite this article

Abstract

THERE are few observations concerning the effect of nutritional state on human hepatitis. These have produced conflicting results1,2. As all attempts to culture the virus of human infectious hepatitis have been unsuccessful3 the effect of dietary deficiency on mouse hepatitis was investigated. M.H.V.3 virus isolated by Dick, Niven and Gledhill4 was selected. This virus is uniformly fatal to weanling mice but mortality decreases with age. Swiss Webster strain mice (Budd Mountain Farm, Chester, New Jersey) were used. The severity of M.H.V.3 infection is enhanced by Eperythrozoon coccoides. Peripheral blood films from the experimental mice showed they did not carry Eperythrozoon coccoides.

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Authors and Affiliations

  1. Department of Pathology, Dalhousie University, Halifax, Nova Scotia

    BORIS RUEBNER & JAMES L. BRAMHALL

Authors
  1. BORIS RUEBNER
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  2. JAMES L. BRAMHALL
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RUEBNER, B., BRAMHALL, J. Effect of Dietary Protein on the Severity of Experimental Mouse Hepatitis. Nature 183, 609–610 (1959). https://doi.org/10.1038/183609a0

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