Abstract
EARLY studies1 of the metabolism of the polycyclic hydrocarbon 3 : 4 benzypyrene showed that this compound was converted within mouse and rat tissues to one or other of two water-soluble derivatives. These were characterized physically, but not chemically identified, and for convenience in later work were labelled as BpX 1 and BpX 2.
Similar content being viewed by others
Article PDF
References
Weigert, F., and Mottram, J. C., Cancer Res., 6, 97 (1946).
Calcutt, G., and Payne, S., Brit. J. Cancer, 8, 554, 561, 710 (1954).
Calcutt, G. (unpublished results).
Harper, K. H., Brit. J. Cancer (in the press).
Bernstein, S., and McGilvery, R. W., J. Biol. Chem., 198, 195 (1952).
De Meio, R. H., Wizerkaniuk, M., and Fabiani, E., J. Biol. Chem., 203, 257 (1953).
Dutton, G. J., and Storey, I. D. E., Biochem. J., 57, 275 (1954).
Strominger, J. L., Kalckar, H. M., Axelrod, J., and Maxwell, E. S., J. Amer. Chem. Soc., 76, 6411 (1954).
Dutton, G. J., Biochem. J., 64, 693 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HARPER, K., CALCUTT, G. Glucuronide and Sulphate Conjugation in vivo and in vitro . Nature 183, 463 (1959). https://doi.org/10.1038/183463b0
Issue Date:
DOI: https://doi.org/10.1038/183463b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.