Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Recovery of Injected Progesterone and its Relation to the Onset of Human Labour

Abstract

THE conception that progesterone is the hormone responsible for the maintenance and therefore secondarily also for the onset of labour is based on several important findings: the indispensability of the corpus luteum for pregnancy in the rabbit1; the extraction of the effective substance from corpora lutea2; the role of progesterone in the implantation and early development of the fertilized ovum3; the excretion of progesterone as urinary pregnanediol and the relation between pregnanediol output and the prognosis of pregnancy4; finally, the elucidation of the mechanism of the endocrine control of the pregnant rabbit uterus5–7.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Fraenkel, L., Arch. Gynäk., 91, 705 (1910).

    Article  Google Scholar 

  2. Corner, G. W., and Allen, W. M., Amer. J. Physiol., 88, 340 (1929).

    Google Scholar 

  3. Courrier, R., C.R. Soc. Biol., Paris, 120, 1263 (1935).

    CAS  Google Scholar 

  4. Browne, J. S. L., Henry, J. S., and Venning, E. H., Amer. J. Obstet. Gynec., 38, 927 (1939).

    Article  Google Scholar 

  5. Csapo, A., Amer. J. Anat., 98, 273 (1956).

    Article  CAS  Google Scholar 

  6. Schofield, B. M., J. Physiol., 129, 289 (1955).

    Article  CAS  Google Scholar 

  7. Bengtsson, L. Ph., Amer. J. Obstet. Gynec., 74, 484 (1957).

    Article  CAS  Google Scholar 

  8. Fuchs, F., and Stakeman, G., Amer. J. Obst. et. Gynec. (in the press.).

  9. Bengtsson, L. Ph. (in preparation).

  10. Caldeyro-Barcia, R., and Poseiro, J. J., Ann. N.Y. Acad. Sci., 75, 813 (1958).

    Article  ADS  Google Scholar 

  11. Zarrow, M. X., and Neher, R., Endocrinol., 56, 1 (1955).

    Article  CAS  Google Scholar 

  12. For references, see Trolle, D., Acta Endocrinol., 19, 217 (1955).

    Article  CAS  Google Scholar 

  13. Guterman, H. S., Rec. Prog. Horm. Res., 8, 293 (1953).

    Google Scholar 

  14. Jensen, C. C., Acta Endocrinol., 28, 37 (1958).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BENGTSSON, L. Recovery of Injected Progesterone and its Relation to the Onset of Human Labour. Nature 183, 405–406 (1959). https://doi.org/10.1038/183405b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/183405b0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing