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Measurement of a Staphylococcal Antibody in Human Serum by a Mouse Protection Test

Nature volume 183, pages 1692–1693 (1959)Cite this article

Abstract

THE need for a better understanding of immune phenomena related to staphylococcal infections has been repeatedly emphasized1. In so far as humoral antibodies are concerned, a substantial amount of work has been done only with staphylococcal antitoxins. However, as pointed out by Rountree and Barbour2, this approach has not appeared to be rewarding. It has also been suggested that anti-coagulase may be an important antibody3; but some doubt exists as to the significance of coagulase in staphylococcal infections4,5. Although a promising serological procedure was developed by Rountree and Barbour2, this method was not applied in a study of infections.

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References

  1. “Staphylococcal Infections”, Ann. N.Y. Acad. Sci., 65, 57 (1956).

  2. Rountree, P. M., and Barbour, R. G. H., Australasian Ann. Med., 1, 80 (1952).

    Article  CAS  Google Scholar 

  3. Boake, W. C., J. Immunol., 76, 89 (1956).

    CAS  PubMed  Google Scholar 

  4. Lack, C. H., Ann. N.Y. Acad. Sci., 65, 103 (1956).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Smith, J. M., and Dubos, R. J., J. Exp. Med., 103, 87 (1956).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Raffel, S., “Immunity Hypersensitivity Serology” (Appleton-Century-Crofts, Inc., New York, 1953).

    Google Scholar 

  7. Fisher, M. W., and Manning, M. C., “Antibiotics Annual 1957–1958”, 572 (Medical Encyclopedia, Inc., New York, 1958).

    Google Scholar 

  8. Hunt, G. A., and Moses, A. J., Science, 128, 1574 (1958).

    Article  ADS  CAS  PubMed  Google Scholar 

  9. Miller, L. C., and Tainter, M. L., Proc. Soc. Exp. Biol. Med., 57, 264 (1944).

    Article  Google Scholar 

  10. Perkins, F. T., J. Gen. Microbiol., 19, 540 (1958).

    Article  CAS  PubMed  Google Scholar 

  11. Fisher, M. W., and Manning, M. C., J. Immunol., 81, 29 (1958).

    CAS  PubMed  Google Scholar 

  12. Jensen, K., Acta Path. Microbiol. Scand., 44, 421 (1958).

    Article  Google Scholar 

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Authors and Affiliations

  1. Research Laboratories, Parke, Davis and Co., Detroit, Michigan

    MYRON W. FISHER

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  1. MYRON W. FISHER
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FISHER, M. Measurement of a Staphylococcal Antibody in Human Serum by a Mouse Protection Test. Nature 183, 1692–1693 (1959). https://doi.org/10.1038/1831692a0

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