Abstract
IT is well known that intermedin, a secretion of the pituitary, is responsible for the dispersion of the pigment in the melanocytes of frogs. The identity of the secretion has remained a mystery; indeed, there are few compounds capable of causing the darkening of hypophysectomized frogs.
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References
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Weissbach, H., Waalkes, T. P., and Udenfriend, S., J. Biol. Chem., 230, 865 (1958).
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DAVEY, K. Serotonin and Change of Colour in Frogs. Nature 183, 1271–1272 (1959). https://doi.org/10.1038/1831271a0
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DOI: https://doi.org/10.1038/1831271a0
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