Abstract
VARIOUS studies have shown that the differential urinary excretion of β-amino-isobutyric acid is under genetic control1–4. Family data indicate that a single major gene pair is responsible for most of the variation in differential excretion of β-amino-isobutyric acid, with high excretors being homozygous for a single recessive gene and low excretors either heterozygous or homozygous for the dominant allele. Further investigations have demonstrated marked variation in the frequency of high and low excretors in different races and have indicated the value of this character in genetical-anthropological work5,6.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Harris, H., Ann. Eugenics, 18, 43 (1953).
Calchi-Novati, C., Ceppellini, R., Biancho, J., Silvestroni, E., and Harris, H., Ann. Eugenics, 18, 335 (1954).
Gartler, S. M., Amer. J. Human Genetics, 8, 120 (1956).
Gartler, S. M., Firschein, I. L., and Kraus, B. S., Amer. J. Human Genetics, 9, 200 (1957).
Gartler, S. M., Firschein, I. L., and Gidaspow, T., Acta Genetica and Statistica Medica, 6, 435 (1956).
Sutton, H. G., and Clark, P. J., Amer. J. Phys. Anthrop., New Series, 13, 53 (1955).
Fink, Kay, J. Biol. Chem., 218, 9 (1956).
Gartler, S., Proc. Tenth Intern. Cong. Genetics, 2, 94 (Univ. of Toronto, 1958).
Cocharane, P., Allen, F. H., Allison, A. C., and Blumberg, B. S. (in preparation).
Gartler, S. M., Arch. Biochem. and Biophys. (in the press).
Newman, S., Amer. Anthropologist, 56, 626 (1954).
Sapir, E., Amer. Anthropologist, 38, 224 (1936).
Kraus, B. C., and White, C. B., Amer. Anthropologist, 58, 1017 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ALLISON, A., BLUMBERG, B. & GARTLER, S. Urinary Excretion of β-Amino-isobutyric Acid in Eskimo and Indian Populations of Alaska. Nature 183, 118–119 (1959). https://doi.org/10.1038/183118a0
Issue Date:
DOI: https://doi.org/10.1038/183118a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
