Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Thyroxine-releasing Effect of Salicylate and of 2,4-Dinitrophenol

Abstract

THE fact that salicylate increases the oxygen consumption in man was first observed by Denis and Means1 in 1916. This observation has since been corroborated by several other investigators2. The oxygen consumption of tissues removed from animals treated with salicylate is likewise increased3.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Denis, W., and Means, J. H., J. Pharmacol. Exp. Therap., 8, 273 (1916).

    CAS  Google Scholar 

  2. Austen, F. K., Rubini, M. E., Meroney, W. H., and Wolff, J., J. Clin. Invest., 37, 1131 (1958).

    Article  CAS  Google Scholar 

  3. Brody, T. M., J. Pharmacol. Exp. Therap., 117, 39 (1956).

    CAS  Google Scholar 

  4. Wolff, J., and Austen, F., J. Clin. Invest., 37, 1144 (1958).

    Article  CAS  Google Scholar 

  5. Wolff, J., Rubin, L., and Chaikoff, I. L., J. Pharmacol. Exp. Therap., 98, 45 (1950).

    CAS  Google Scholar 

  6. Goldberg, R. C., Wolff, J., and Greep, R. O., Endocrinol., 56, 560 (1955).

    Article  CAS  Google Scholar 

  7. Robbins, J., and Rall, J. E., “Rec. Prog. Horm. Res.”, 13, 161 (1957).

    CAS  Google Scholar 

  8. Christensen, L. K., Scand. J. Lab. Clin. Invest. (in the press).

  9. Christensen, L. K., Scand. J. Lab. Clin. Invest., 10, 211 (1958).

    Article  CAS  Google Scholar 

  10. Witter, R. F., Newcomb, E. H., and Stolz, E., J. Biol. Chem., 202, 291 (1953).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CHRISTENSEN, L. Thyroxine-releasing Effect of Salicylate and of 2,4-Dinitrophenol. Nature 183, 1189–1190 (1959). https://doi.org/10.1038/1831189a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1831189a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing