Letter | Published:

Determination of Epinephrine and Related Compounds on Paper Chromatograms


THE most sensitive chemical method for determining epinephrine in solution is the reaction with ethylenediamine. The reaction yields a number of products, several of which are fluorescent. These substances can be used for quantitative measurement. Nor-epinephrine produces a fluorescence of different colour so that mixtures of the two compounds can be determined by the selection of appropriate filters in measuring the fluorescent light1.

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  1. 1

    Malherbe, H., and Bone, A. D., Biochem. J., 51, 311 (1952).

  2. 2

    Brown, J. A., and Marsh, M. M., Anal. Chem., 25, 1865 (1953).

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