Abstract
THE action of sulphanilamide, an antivitamin of p-amino-benzoic acid, has been traced to an impairment of the synthesis of methionine and adenine, besides some other compounds1. In some cases p-amino-benzoic acid could reverse the inhibitory effects of sulphanilamide, whereas folio acid could not2. In our present work, we studied the reversal of the toxicity of sulphanilamide in Neurospora crassa 8a (wild) and the substitution of p-amino-benzoie acid in a strain without the acid (No. 1633) of the same mould.
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SANKAR, D. Para-Amino-Benzoic Acid and Sulphanilamide in the Nutrition of Neurospora crassa . Nature 181, 629–630 (1958). https://doi.org/10.1038/181629a0
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DOI: https://doi.org/10.1038/181629a0
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