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Isomeric Chondroitin Sulphates

Nature volume 181, pages 421–422 (1958)Cite this article

Abstract

A RECENT communication1 claims to “confirm Meyer's hypothesis that chondroitin sulphates A and C are only two fractions of the same polydisperse substance”. Apparent lack of agreement in nomenclature2–4 further emphasizes the need for clear differentiation of the isomeric chondroitin sulphates of connective tissue. These three substances, chondroitin sulphate A, chondroitin sulphate B and chondroitin sulphate C, respectively, in the nomenclature of Meyer et al. 2, have been found to be linear polyelectrolytes with similar chain configuration-charge relationships. Chondroitin sulphates A and C have been clearly distinguished as molecular individuals by comparison of molecular constants and physical properties.

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References

  1. Bernardi, G., Happey, F., and Naylor, A., Nature, 180, 1341 (1957).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Meyer, K., Davidson, E., Linker, A., and Hoffman, P., Biochim. Biophys. Acta, 21, 506 (1956).

    Article  CAS  PubMed  Google Scholar 

  3. Orr, S. F. D., Biochim. Biophys. Acta, 14, 173 (1954).

    Article  CAS  PubMed  Google Scholar 

  4. Hall, D. A., Lloyd, P. F., Happey, F., Horton, W. G., and Naylor, A., Nature, 179, 1078 (1957).

    Article  CAS  PubMed  Google Scholar 

  5. Mathews, M. B., and Dorfman, A., Arch. Biochem. Biophys., 42, 41 (1953).

    Article  CAS  PubMed  Google Scholar 

  6. Marbet, R., and Winterstein, A., Helv. Chim. Acta, 34, 2311 (1951).

    Article  CAS  Google Scholar 

  7. Naganishi, K., Takahashi, N., and Egami, F., Bull. Chem. Soc. Japan, 29, 434 (1956).

    Article  Google Scholar 

  8. Schiller, S., Mathews, M. B., Jefferson, H., Ludowieg, J., and Dorfman, A., J. Biol. Chem., 211, 717 (1954).

    CAS  PubMed  Google Scholar 

  9. Jeanloz, R. W., Stoffyn, P. J., and Tremege, M., Federation Proc., 16, 201 (1957). Cifonelli, J. A., Ludowieg, J., and Dorfman, A., Fed. Proc., 16, 165 (1957).

    Google Scholar 

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Author notes

  1. MARTIN B. MATHEWS

    Present address: Wheatstone Physics Laboratory, King's College, London, W.C.2.

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  1. LaRabida-University of Chicago Institute and the Department of Biochemistry, University of Chicago,

    MARTIN B. MATHEWS

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  1. MARTIN B. MATHEWS
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MATHEWS, M. Isomeric Chondroitin Sulphates. Nature 181, 421–422 (1958). https://doi.org/10.1038/181421a0

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