A Comparative Biochemical Study of Nucleohistones from Different Vertebrates

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RESULTS recently reported by Crampton et al. 1 lead those authors to the conclusion that the nucleohistones extracted from the different tissues of the same animal are very similar in composition. Our own investigations on different organs of the calf confirm these results (Table 1, Fig. 1).

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  1. 1

    Crampton, C. F., Stein, W. H., and Moore, S., J. Biol. Chem., 225, 363 (1957).

  2. 2

    Signer, R., and Schwander, H., Helv. Chim. Acta, 32, 853 (1949).

  3. 3

    Chargaff, E., in “The Nucleic Acids”, 1, 307 (Academic Press, New York, 1955).

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VENDRELY, R., KNOBLOCH, A. & MATSUDAIRA, H. A Comparative Biochemical Study of Nucleohistones from Different Vertebrates. Nature 181, 343 (1958) doi:10.1038/181343a0

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