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Formation of Histamine-containing Dinucleotides by Enzymatic Interaction of Histamine and Coenzyme I

Abstract

DIPHOSPHOPYRIDINE nucleotide (coenzyme I) reacts, in the presence of a soluble purified preparation of diphosphopyridine nucleotidase1, with 4-amino-5-carboxamido-imidazole yielding the pyrophosphate of adenosine-5′-phosphate and of the 4-amino-5-carboxamido-imidazole ribotide2,3. The latter may serve as a precursor in the biosynthesis of inosinic acid4.

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ALIVISATOS, S. Formation of Histamine-containing Dinucleotides by Enzymatic Interaction of Histamine and Coenzyme I. Nature 181, 271–272 (1958). https://doi.org/10.1038/181271a0

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