Abstract
IN a research programme on the physiological effects of ozone, an attempt was made to determine the mechanism of ozone poisoning by studying chemical protection before exposure. Swiss albino mice were treated by intraperitoneal injections of the test chemical followed by exposure for 3 hr. to a concentration of 8—25 p.p.m. of ozone. This ozone concentration caused death in 10–80 per cent of the animals1. Usually 10 control (no prior treatment) animals and 10 treated animals were exposed together in a large glass chamber 12.5 in. × 30 in. × 16 in. to ozone generated by a water-cooled corona discharge type of ozonizer. The results of these experiments are recorded in Table 1.
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MITTLER, S. Protection against Death due to Ozone Poisoning. Nature 181, 1063–1064 (1958). https://doi.org/10.1038/1811063a0
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DOI: https://doi.org/10.1038/1811063a0
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