Abstract
THE reaction of ethylene diamine with epinephrine (and norepinephrine) leads to the formation of a highly fluorescent material which is used for the estimation of catechol amines in biological fluids according to a procedure first described by Weil-Malherbe and Bone1 and slightly modified by a number of other workers.
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References
Weil-Malherbe, H., and Bone, A. D., Biochem. J., 51, 311 (1952).
Erne, K., and Canbäck, T., J. Pharm. Pharmacol., 7, 248 (1955).
Valk, A. de T., and Price, H. L., J. Clin. Invest., 35, 837 (1956).
Mangan, G. F., and Mason, J. W., Science, 126, 562 (1957).
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NADEAU, G., JOLY, L. & SOBOLEWSKI, G. Influence of Metallic Ions on the Reaction of Ethylene Diamine with Epinephrine and Norepinephrine. Nature 181, 1061 (1958). https://doi.org/10.1038/1811061a0
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DOI: https://doi.org/10.1038/1811061a0
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