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Microchemical Method for the Determination of Sakaguchi-positive Antibiotics

Abstract

ANTIBIOTICS of actinomycete origin containing a guanidine group (such as streptomycin and viomycin) are known to have an antitubercular action. Recently a new antibiotic, primycin, was described1 as an agent active against various mycobacteria and Gram-positive pathogens (0.02 µgm./ml.), and also giving a positive Sakaguchi reaction.

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SZILÁGYI, I., SZABÓ, I. Microchemical Method for the Determination of Sakaguchi-positive Antibiotics. Nature 181, 52–53 (1958). https://doi.org/10.1038/181052a0

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