Abstract
Crick and Watson1 suggested that a small virus particle contains identical protein sub-units packed together with cubic symmetry, and they went on to predict from this that the virus particle itself might be polyhedral. Electron micrographs have since shown that various viruses do give hexagonal images. This is clearly the case, for example, for the plant virus of turnip yellow mosaic2 and for an insect virus that infects the larvæ of the crane fly3. We now report finding a similar hexagonal shape for the particles of adenovirus which is a human pathogen.
Similar content being viewed by others
Article PDF
References
Crick, F. H. C., and Watson, J. D., Nature, 177, 473 (1956).
Kaesberg, P., Science, 124, 626 (1956).
Williams, R. C., and Smith, K. M., Nature, 179, 119 (1957).
Morgan, C., Howe, C., Rose, H. M., and Moore, D. H., J. Biophys. Biochem. Cytol., 2, 351 (1956).
Brandon, F. B., Taylor, A. R., Patterson, M., and McLean, jun., I. W., Fed. Proc., 16, 407 (1957).
Bradley, D. E., J. App. Phys., 27, 1399 (1956).
Peters, D., and Stoeckenius, W., Nature, 174, 224 (1954).
Valentine, R. C., and Isaacs, A., J. Gen. Microbiol., 16, 195 (1957).
Valentine, R. C., and Isaacs, A., J. Gen. Microbiol., 16, 680 (1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
VALENTINE, R., HOPPER, P. Polyhedral Shape of Adenovirus Particles as shown by Electron Microscopy. Nature 180, 928 (1957). https://doi.org/10.1038/180928a0
Issue Date:
DOI: https://doi.org/10.1038/180928a0
This article is cited by
-
Classification of an avian virus by electron microscopy
Archiv f�r die gesamte Virusforschung (1967)
-
Electron-dense Crystallites in Nuclei of Human Amnion Cells infected with Measles Virus
Nature (1960)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.