Letter | Published:

Ultrastructure of Erythrocytes in Severe Scurvy

Nature volume 180, pages 812813 (19 October 1957) | Download Citation

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Abstract

A SURVEY of the literature has revealed that anæmia complicates 70 per cent of all clinical cases of severe scurvy1. The increased urobilinogenæmia of scurvy is evidence of an accelerated disintegration of erythrocytes2. These factors, combined with the recent demonstration of a hæmolytic process in human scorbutic patients3, prompted us to study the effects of vitamin C deficiency on the ultrastructure of the erythrocytes of animals suffering from scurvy.

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References

  1. 1.

    , , and , J. Missouri Med. Assoc., 43, 756 (1952).

  2. 2.

    , , and , J. Lab. Clin. Med., 31, 609 (1946).

  3. 3.

    , Brit. Med. J., ii, 1353 (1953).

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Affiliations

  1. American College of Cardiology and Elmhurst General Hospital, New York, and Research Laboratories, National Drug Co., Philadelphia. May 13.

    • BRUNO KISCH
    •  & GUSTAV J. MARTIN

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DOI

https://doi.org/10.1038/180812a0

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